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Previous Volume 354:2514-2515 June 8, 2006 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: A 56-year-old woman had a two-year history of refractory celiac disease for which she had taken prednisone (20 mg per day) for the previous six months, during which time her condition had worsened despite a gluten-free diet. Duodenal biopsy showed severe atrophy with crypt hyperplasia and increased intraepithelial lymphocyte counts. On immunohistochemical analysis, the cytoplasm was positive for CD3 and negative for CD4 and CD8 (Figure 1). Flow-cytometric analysis of intraepithelial lymphocytes showed that more than 50 percent of the cells expressed T-cell receptor (TCR). In addition, we identified a second aberrant population of . . . [Full Text of this Article]

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Alemtuzumab for Refractory Celiac Disease
Verbeek W. H.M., Mulder C. J.J., Zweegman S., Vivas S., Ruiz de Morales J. M., Ramos F.
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N Engl J Med 2006; 355:1396-1397, Sep 28, 2006. Correspondence

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