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Editorial
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Volume 354:2712-2714 June 22, 2006 Number 25
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Connexins, Conduction, and Atrial Fibrillation
Jeffrey E. Saffitz, M.D., Ph.D.

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-Related Article
 by Gollob, M. H.
-PubMed Citation
Atrial fibrillation has always been the little sister to its ventricular counterpart — but during the past decade, it has captured our attention, mainly because it is so common. Atrial fibrillation affects nearly 2.5 million Americans, and this number could double over the next 50 years as the population ages.1 Although not the killer that ventricular fibrillation is, atrial fibrillation is by no means benign. Roughly 15 percent of strokes in the United States have been attributed to this arrhythmia.2

The pathogenesis of atrial fibrillation is complex, even as compared with the other tachyarrhythmias. Atrial fibrillation arises from dynamic interactions . . . [Full Text of this Article]


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From the Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School — both in Boston.


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