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Previous Volume 354:2794-2801 June 29, 2006 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 26-year-old woman with a summer home on Long Island, New York, had a low-grade fever, malaise, arthralgias, headache, and neck pain one week after removing a tick from her thigh. Examination reveals a nontender oval (8 by 12 cm), homogeneously erythematous lesion at the site of the tick bite, consistent with erythema migrans. How should this case be managed? What if . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Diagnosis

Coinfection

Treatment

Prevention

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Division of Infectious Diseases, Department of Medicine, New York Medical College, Valhalla. Address reprint requests to Dr. Wormser at Rm. 245, Munger Pavilion, New York Medical College, Valhalla, NY 10595, or at gary_wormser@nymc.edu.

This article has been cited by other articles:

• Hildenbrand, P., Craven, D.E., Jones, R., Nemeskal, P. (2009). Lyme Neuroborreliosis: Manifestations of a Rapidly Emerging Zoonosis. Am. J. Neuroradiol. 30: 1079-1087 [Abstract] [Full Text]  
• Morrison, C., Seifter, A., Aucott, J. N. (2009). Unusual Presentation of Lyme Disease: Horner Syndrome with Negative Serology. J Am Board Fam Med 22: 219-222 [Abstract] [Full Text]  
• Tonks, A. (2007). Lyme wars. BMJ 335: 910-912 [Full Text]  
• Grab, D. J., Nyarko, E., Barat, N. C., Nikolskaia, O. V., Dumler, J. S. (2007). Anaplasma phagocytophilum-Borrelia burgdorferi Coinfection Enhances Chemokine, Cytokine, and Matrix Metalloprotease Expression by Human Brain Microvascular Endothelial Cells. CVI 14: 1420-1424 [Abstract] [Full Text]  
• Tibbles, C. D., Edlow, J. A. (2007). Does This Patient Have Erythema Migrans?. JAMA 297: 2617-2627 [Abstract] [Full Text]  
• KRAUSE, P. J., FOLEY, D. T., BURKE, G. S., CHRISTIANSON, D., CLOSTER, L., SPIELMAN, A., THE TICK-BORNE DISEASE STUDY GROUP, (2006). REINFECTION AND RELAPSE IN EARLY LYME DISEASE. Am J Trop Med Hyg 75: 1090-1094 [Abstract] [Full Text]