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Volume 354:2830-2832 June 29, 2006 Number 26
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Enoxaparin versus Unfractionated Heparin in ST-Elevation Myocardial Infarction

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 by Antman, E. M.
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To the Editor: On behalf of the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction Treatment (ExTRACT)–Thrombolysis in Myocardial Infarction (TIMI) 25 Study investigators, Antman et al. (April 6 issue)1 compared the use of seven days of enoxaparin with 48 hours of unfractionated heparin in patients receiving fibrinolysis for ST-elevation myocardial infarction. The longer duration of treatment with enoxaparin was found to be superior to the short course of treatment with unfractionated heparin, although the longer treatment was associated with an increase in major bleeding episodes. One may conclude from this study that enoxaparin provides superior anticoagulation to that of . . . [Full Text of this Article]


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