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Volume 354:2832 June 29, 2006 Number 26
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Prevalence of Monoclonal Gammopathy of Undetermined Significance

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 by Kyle, R. A.
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To the Editor: Kyle et al. (March 30 issue)1 cite a study that my colleagues and I conducted2 that was, contrary to their statement, population based. We found a population prevalence of monoclonal gammopathy of undetermined significance (MGUS) of 3.6 percent among whites. Among the 916 blacks in our study, the prevalence of MGUS was 8.4 percent. The difference in prevalence between whites and blacks was significant (P<0.001). The study in Olmsted County, Minnesota, in which 97 percent of the subjects were white, could not reveal the higher prevalence of MGUS in blacks as compared with whites.


Harvey Jay Cohen, . . . [Full Text of this Article]




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