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After Ernest A. McCulloch and James E. Till received the Albert Lasker Medical Research Award in Basic Research in 2005, they wrote a commentary in Nature Medicine. In it, they asked themselves, "Why now?" After all, their papers on the colony-assay model of cells from the mouse spleen which described for the first time the hematopoietic stem cell of the bone marrow as a cell that is capable of both self-renewal and differentiation are more than 40 years old. This book seems to have the answers.
Stem cells appear to be present both in bone marrow and in
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