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A 63-year-old woman was admitted to the hospital for evaluation of a pancreatic mass.
Four months before admission, the patient noticed dysuria and dark urine. The results of urinalysis showed 3+ bilirubin and 2+ occult blood and were otherwise normal. A urinary tract infection was diagnosed, and levofloxacin was prescribed. A urine culture subsequently showed no growth of bacteria. Five days after the urinalysis, she went to a local hospital emergency department, where she said that she had had dark urine, pruritus, and intermittent epigastric pain for the preceding 10 days; a weight loss of 5 kg during the past
Differential Diagnosis
Neoplastic Causes of Bile-Duct Obstruction
Non-Neoplastic Causes of Biliary Obstruction
Clinical Diagnosis
Dr. Robert H. Schapiro's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Gastrointestinal Unit (R.H.S.) and the Departments of Radiology(M.M.M.) and Pathology (J.M.), Massachusetts General Hospital; and the Departments of Medicine (R.H.S.), Radiology (M.M.M.) and Pathology (J.M.), Harvard Medical School.
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