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Correspondence
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Volume 354:420 January 26, 2006 Number 4
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Cabergoline and Mitral Regurgitation

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To the Editor: Pinero et al. (Nov. 3 issue)1 describe a 74-year-old man with Parkinson's disease in whom severe mitral regurgitation developed after a relatively short course of treatment with cabergoline, an ergot dopamine agonist. Cabergoline is used in different settings at different doses. In patients with Parkinson's disease, the usual daily dose ranges from 2 to 6 mg,2 whereas in hyperprolactinemia, the weekly dose ranges from 0.25 to 3.5 mg.3 So far, fibrotic reactions and valvular heart disease due to the use of ergot dopamine agonists have been reported almost exclusively in patients with Parkinson's disease and thus could . . . [Full Text of this Article]


Related Letters:

Cabergoline-Related Severe Restrictive Mitral Regurgitation
Pinero A., Marcos-Alberca P., Fortes J.
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N Engl J Med 2005; 353:1976-1977, Nov 3, 2005. Correspondence



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