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Previous Volume 354:516-518 February 2, 2006 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Among the critically ill, elevations in blood glucose, a marker previously ignored or described as adaptive, became a major therapeutic target after a 2001 study indicated a mortality benefit of intensive insulin therapy among patients in a surgical intensive care unit (ICU).¹ Concern has arisen about that study because of the relatively high mortality in relation to the severity of illness among patients in the control group; the frequent administration of parenteral calories to critically ill patients, a practice that is uncommon at other centers; a preponderance of patients who had cardiac surgery in the single center where the study . . . [Full Text of this Article]

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From the Pulmonary and Critical Care and Sleep Medicine Divisions, Brigham and Women's Hospital and Harvard Medical School — both in Boston.

Related Letters:

Intensive Insulin Therapy in the Medical ICU
Hammer L., Dessertaine G., Timsit J.-F., Aberegg S. K., Tamler R., LeRoith D., Roth J., Van den Berghe G., Wilmer A., Bouillon R., Malhotra A.
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N Engl J Med 2006; 354:2069-2071, May 11, 2006. Correspondence

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