Preeclampsia, either alone or superimposed on another disorder,is a major cause of maternal and fetal death and the leadingcause of premature delivery worldwide.1 Underappreciated isthe strain that preeclampsia places on the health care resourcesof all nations. This disease increases the need for neonatalintensive care; in addition, early birth may lead to healthproblems later in life. Considerable evidence suggests thatpremature delivery increases the incidence of remote cardiovascularand metabolic health problems, which themselves create enormouseconomic health burdens.2,3 Thus, the ability to predict orprevent preeclampsia or the development of therapy that safelyprolongs . . . [Full Text of this Article]
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From the Departments of Obstetrics and Gynecology and Medicine, University of Chicago, Chicago (M.D.L.); MedStar Research Institute, Hyattsville, MD (J.G.U.); and the Departments of Medicine and Obstetrics and Gynecology, Georgetown University, Washington, DC (J.G.U.).
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