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Volume 355:1281-1282 September 21, 2006 Number 12
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Omalizumab for Asthma

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 by Strunk, R. C.
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To the Editor: Strunk and Bloomberg (June 22 issue)1 discuss omalizumab for the treatment of asthma associated with high serum IgE levels. We provided care for a man who received omalizumab and in whom the Churg–Strauss syndrome subsequently developed.

Our patient was a 55-year-old man with a history of asthma who presented with acute onset of numbness and tingling in his extremities. A neurologic examination was notable for hyporeflexia. The patient had a purpuric rash on both lower extremities. A pulmonary examination was unremarkable. The white-cell count was 23.1x103 per microliter with 47% eosinophils. Skin biopsy revealed a . . . [Full Text of this Article]




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