Age-related macular degeneration, a potentially blinding disease,is now epidemic in the developed world. Roughly one in threepeople will be affected to some degree by the age of 75 years.1Medicine's tremendous successes in the battles against cancer,diabetes, hypertension, heart disease, and other common killershave raised the average life expectancy in many countries tomore than 75 years and in so doing have inadvertently delivereda new scourge to mankind.
In this issue of the Journal, de Jong2 discusses age-relatedmacular degeneration as a complex disorder that begins decadesbefore a patient becomes symptomatic, a molecular derangement. . . [Full Text of this Article]
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From the Carver Family Center for Macular Degeneration, Howard Hughes Medical Institute, University of Iowa Carver College of Medicine, Iowa City.
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