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Volume 355:1496-1497 October 5, 2006 Number 14
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Inhaled Carbon and Lung Function in Children

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 by Gauderman, W. J.
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 by Kulkarni, N.
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To the Editor: Kulkarni and colleagues (July 6 issue)1 found that the level of carbon in airway macrophages in children was strongly associated with expiratory flow rates, although in the 64 healthy children with sufficient numbers of airway macrophages for analysis, all these values were within generally acceptable normal limits. Why should this be? We suggest that this finding indicates that an accumulation of particles was a strong indicator of exposure to urban particulate air pollution and that exposure, in turn, is associated with chronic respiratory subclinical bronchiolitis. If so, we suggest that current exposures to urban pollution have to . . . [Full Text of this Article]




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