The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Perspective
FOCUS ON RESEARCH

PreviousPrevious
Volume 355:1522-1523 October 12, 2006 Number 15
NextNext

The Two-Edged Sword of Curing Childhood Cancer
Philip M. Rosoff, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Commentary
-Letters

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-Related Article
 by Oeffinger, K. C.
-PubMed Citation
In the June 3, 1948, issue of the Journal, Sydney Farber and his colleagues reported that they had successfully used aminopterin to induce temporary remission in children with lymphoid leukemia. This exciting article suggested that what had been a uniformly fatal disease might be amenable to treatment and, some dared to hope, cure. Then, in 1970, DeVita and his colleagues at the National Cancer Institute showed that a combination of non–cross-reactive chemotherapeutic agents, the MOPP regimen (mechlorethamine, vincristine, procarbazine, and prednisone), could induce sustained remission in advanced Hodgkin's disease. From such beginnings, an extraordinary success story unfolded, and today, more . . . [Full Text of this Article]


Source Information

Dr. Rosoff is an associate professor of pediatric hematology–oncology at Duke University School of Medicine and director of the Duke University Hospital Program in Clinical Ethics, Durham, NC.


Related Letters:

Survivors of Childhood Cancer
Goodwin T., Oosterhuis B. E., Hayes-Lattin B., the LIVESTRONG Young Adult Alliance , Sharma N., Melgar T., Brands C., Haupt R., Jankovic M., Veerman A. J.P., the International Berlin–Frankfurt–Münster Early and Late Toxicity Educational Committee , Oeffinger K. C., Sklar C. A., Robison L. L., Rosoff P. M.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:191-194, Jan 11, 2007. Correspondence

This article has been cited by other articles:



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.