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A 15 1/2-year-old girl was seen in the outpatient Weight Center of this hospital for the evaluation of severe obesity. She had had a normal gestation without complications and had been adopted during the first month of life. She weighed 3.9 kg at birth and 4.8 kg at 1 month of age. At the age of 1 year, her weight-to-length ratio was in the 75th percentile. At 3 years of age, her body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) was above the 97th percentile. She was referred to a nutritionist. Her
Differential Diagnosis
Obstructive Sleep Apnea
Sequelae
Treatment
Insulin Resistance and Type 2 Diabetes Mellitus
Hypertension and Dyslipidemia
Polycystic Ovary Syndrome
Nonalcoholic Fatty Liver Disease
Causes of Obesity
Discussion of Management
Weight-Loss Strategies
Bariatric Surgery
Anatomical Diagnosis
Source Information
From the Department of Pediatrics (A.G.H., E.S.K.), the Gastrointestinal Unit (L.M.K.), and the Department of Pathology (G.Y.L.), Massachusetts General Hospital; and the Departments of Pediatrics (A.G.H., E.S.K.), Medicine (L.M.K.), and Pathology (G.Y.L.), Harvard Medical School.
Related Letters:
Case 31-2006: A Girl with Severe Obesity
Titomanlio L., Verloes A., Mercier J.-C., Schlegel A., Polotsky A. J., Rieder J., Santoro N., Hoppin A. G., Kaplan L. M.
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N Engl J Med 2007;
356:194-196, Jan 11, 2007.
Correspondence
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