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FOCUS ON RESEARCH Previous Volume 355:1643-1645 October 19, 2006 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Immune thrombocytopenic purpura (ITP) in adults is usually a chronic disease in which a low platelet count often causes mucocutaneous bleeding. ITP is a diagnosis of exclusion. Pseudothrombocytopenia and such disorders as drug-induced thrombocytopenia, microangiopathic thrombocytopenia, bone marrow failure, and congenital thrombocytopenia must be ruled out. The disorder can be primary (idiopathic) or secondary. Secondary ITP is associated with systemic lupus erythematosus, chronic lymphocytic leukemia, lymphoma, HIV infection or full-blown AIDS, hepatitis C infection, and a variety of other disorders.

Multiple mechanisms cause the thrombocytopenia in ITP, so the disorder is likely to be heterogeneous.¹ Over 50 years ago, Harrington . . . [Full Text of this Article]

Source Information

Dr. Bromberg is an associate professor of medicine and pharmacology at Temple University School of Medicine, Philadelphia.

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