FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 355:1834-1836 October 26, 2006 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

To the Editor: We report two cases of hypomagnesemic hypoparathyroidism associated with the use of proton-pump inhibitors, in which patients presented with carpopedal spasm in association with severe hypomagnesemia and hypocalcemia without an appropriate increase in the level of parathyroid hormone.

Patient 1 was a 51-year-old premenopausal woman who had been taking omeprazole for more than a year (at a dose of 20 mg twice daily) and who presented with carpopedal and truncal spasm. She began receiving 2.4 g of elemental calcium per day and, later, high-dose magnesium (Figure 1A). Fourteen months later, omeprazole was discontinued, and ranitidine . . . [Full Text of this Article]

This article has been cited by other articles:

• Broeren, M. A.C., Geerdink, E. A.M., Vader, H. L., van den Wall Bake, A. W. L. (2009). Hypomagnesemia Induced by Several Proton-Pump Inhibitors. ANN INTERN MED 151: 755-756 [Full Text]  
• Shabajee, N, Lamb, E J, Sturgess, I, Sumathipala, R W (2008). Omeprazole and refractory hypomagnesaemia. BMJ 337: a425-a425 [Full Text]