This Journal feature begins with a case vignette highlightinga common clinical problem. Evidence supporting various strategiesis then presented, followed by a review of formal guidelines,when they exist. The article ends with the author's clinicalrecommendations.
A 53-year-old woman with asthma and multilobar pneumonia isadmitted with respiratory failure. She is intubated and treatedwith antibiotics, albuterol, and methylprednisolone. A randomblood glucose measurement obtained on admission shows a levelof 183 mg per deciliter (10.2 mmol per liter). After 3 hoursin the intensive care unit, she has a capillary glucose levelof 264 mg per deciliter . . . [Full Text of this Article]
The Clinical Problem
Strategies and Evidence
Factors Affecting Treatment Strategies
Oral Agents
Insulin
Guidelines
Areas of Uncertainty
Conclusions and Recommendations
Source Information
From the Section of Endocrinology, Yale University School of Medicine, New Haven, CT.
Address reprint requests to Dr. Inzucchi at the Section of Endocrinology, Yale University School of Medicine, 333 Cedar St., LLCI-101, New Haven, CT 06520-8020, or at silvio.inzucchi@yale.edu.
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