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Previous Volume 355:1936-1938 November 2, 2006 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the Case Record presented in the August 10 issue,¹ which describes the management of an overdose of amlodipine, Harris cites Kline et al.² and states that "data from studies in animals and humans support the administration of insulin while maintaining normal blood glucose levels (hyperinsulinemia–euglycemia therapy) as first-line therapy in poisoning with calcium-channel blockers." Kline et al. reported the effects of this therapy in canines only and concluded that, as compared with glucagon, calcium chloride, or epinephrine, hyperinsulinemia–euglycemia therapy prolonged survival. In humans, however, this therapy has been reported to be successful only in single cases . . . [Full Text of this Article]

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