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Correspondence
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Volume 355:1938-1940 November 2, 2006 Number 18
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Tracheal Replacement with Aortic Allografts

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To the Editor: We report tracheal replacement with fresh aortic allografts in two patients with large chemotherapy-resistant and radiotherapy-resistant tumors (mucoepidermoid and adenoid cystic carcinomas). These interventions were made on the basis of the extent of the lesions (making them unresectable), the severity of each patient's clinical condition, the lack of alternative treatment options, and the success of this intervention in sheep and pig models.1,2,3,4 The transplantation was approved for each patient by the French National Bioethics Advisory Commission. Both procedures were performed through a median cervicosternotomy. In the first patient, tumor dissection was followed by sectioning of the trachea . . . [Full Text of this Article]


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