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Volume 355:2045-2046 November 9, 2006 Number 19
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A New Approach to Drug Development

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by Wood, A. J.J.
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To the Editor: In his Sounding Board article calling for changes in the drug-approval process, Wood (Aug. 10 issue)1 does not consider a very important concept. What if basic research points toward a simpler and cheaper way to treat, control, or cure one of the chronic disorders? The history of the discovery of niacin as a cure for pellagra is a prime example of such an effort. We cannot expect pharmaceutical companies to take on such tasks.


Harry E. Guda, M.D.
Basic Brain Research
Rockbridge, OH 43149

  1. Wood AJJ. A proposal for radical changes in the drug-approval process. N Engl J Med 2006;355:618-623. [Free Full Text]
 
To the Editor: Although Wood's ideas for changing the drug-approval process are interesting, . . . [Full Text of this Article]



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