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Previous Volume 355:213-215 July 13, 2006 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Mutations in the epidermal growth factor receptor gene (EGFR) occur in 10 to 20 percent of non–small-cell lung cancers, specifically adenocarcinomas, and are associated with the response to EGFR tyrosine kinase inhibitors (erlotinib and gefitinib).¹ However, the results of screening of small-cell lung cancers for EGFR mutations have been negative.² Thus, small-cell lung cancers are not routinely tested for EGFR mutations, nor have they been systematically evaluated for responsiveness to EGFR tyrosine kinase inhibitors.

A 45-year-old woman who had never smoked and who had masses in the right lung, pleura, mediastinum, and frontal lobe was . . . [Full Text of this Article]

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