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Previous Volume 355:2266-2267 November 23, 2006 Number 21 Next

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By Josef Donnerer and Fred Lembeck. 228 pp., illustrated. Basel, Switzerland, Karger, 2006. $142. ISBN 3-8055-8004-5.

This book recalls the discovery of the way in which impulses are transmitted from one nerve cell to another. By 1900, it had become clear that the nervous system consists of separate nerve cells rather than having a syncytial structure. The next problem was determining how nerve cells communicate: by the transmission of electrical signals across the synapse (the theory supported by the faction known as the "sparks") or through transmitter molecules (the theory supported by the group known as the "soups").

In 1914, Henry Hallett Dale (1875–1968), working in the Wellcome Laboratories in London, showed that the actions of . . . [Full Text of this Article]

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