Mostly unrecognized before 1980, nonalcoholic fatty liver diseasenow affects all fields of clinical medicine and is the mostcommon form of chronic liver disease in the United States.1The prevalence of this disorder is expected to increase withthe epidemic of obesity and type 2 diabetes mellitus. Its prevalencein non-Western countries is also increasing,2 in large partbecause of globalization of the Western diet. Data based onultrasonographic studies and serum enzyme measurements indicatethat the prevalence of nonalcoholic fatty liver disease in thegeneral U.S. population is approximately 30%.1,3 This suggeststhat there may be as many . . . [Full Text of this Article]
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From the Department of Gastroenterology and Hepatology, Cleveland Clinic, and the Cleveland Clinic Lerner College of Medicine, Case Western Reserve University both in Cleveland.
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