The term "autoimmune pancreatitis" (or "autoimmune-related pancreatitis")was introduced by Yoshida et al. in 1995 to describe the formof chronic pancreatitis that is associated with autoimmune manifestationsrevealed on laboratory, histologic, and clinical testing.1 Inthe past 10 years, interest in autoimmune pancreatitis has grownbecause of an increasing ability to diagnose it with the useof new markers of disease and pancreatic biopsy. Treatment ofautoimmune pancreatitis with corticosteroids leads to the rapidand sustained resolution of pancreatic mass lesions, biliaryobstruction, and pancreatic-duct strictures, which has stimulatedwidespread interest in this condition from gastroenterologists,endoscopists, pathologists, and . . . [Full Text of this Article]
Definition
Epidemiology
Cause and Pathogenesis
Pathology
Clinical Features
Diagnostic Imaging
Diagnostic Criteria
Diagnostic and Therapeutic Approaches
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From the Departments of Medicine (Gastrointestinal Unit) (D.L.F., W.R.B.), Radiology (D.S.), and Pathology (V.D.), Massachusetts General Hospital, Boston.
Address reprint requests to Dr. Brugge at the Gastrointestinal Unit, Blake 452c, Massachusetts General Hospital, 55 Fruit St., Boston, MA 02114, or at wbrugge@partners.org.
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Autoimmune Pancreatitis
Ralli S., Lin J., Farrell J., Leclercq P., Meurisse N., Honore P., Raina A., Yadav D., Krasinskas A. M., Brugge W. R.
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N Engl J Med 2007;
356:1586-1587, Apr 12, 2007.
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