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Previous Volume 355:2710-2711 December 21, 2006 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Edited by Karim Fizazi. 240 pp., illustrated. New York, Informa Healthcare/Taylor & Francis, 2006. $199.95. ISBN 0-8247-2799-1.

Carcinoma of an unknown primary site (CUP) is a common and often puzzling condition. It is probably underdiagnosed because clinicians may be reluctant to acknowledge the uncertainty of such a diagnosis (a "best guess" diagnosis may be applied). Yet CUP is a specific entity that demands clinical problem solving once the histopathology and distribution of the metastases have been established. Patients with visceral or skeletal metastases are expected to survive only a few months, whereas patients with only lymph node metastases may survive for many years.

The definition of CUP is metastatic carcinoma detected when the primary site of origin . . . [Full Text of this Article]

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