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Volume 355:2794-2795 December 28, 2006 Number 26
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Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics

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By Frederic Lawrence Holmes. Edited by William C. Summers. 334 pp., illustrated. New Haven, CT, Yale University Press, 2006. $50. ISBN 0-300-11078-2.

In January 1954, Seymour Benzer began one of the most beautiful experiments in 20th-century biology. Officially, he was a professor in the department of physics at Purdue University. In reality, he had long since left physics to explore the nature of the gene. Benzer was a member of a loose network of scientists known as the phage group: he studied genes using bacteria and their parasites, bacteriophages. While preparing a classroom phage demonstration at Purdue, he hit on a way to map the genome of a bacteriophage in unprecedented detail.

Benzer's now-famous map — on which he worked furiously for . . . [Full Text of this Article]




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