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Twenty years ago, the American Heart Association sponsored a symposium in Boston that constituted the first national meeting focused exclusively on the molecular biology of cardiovascular disease. Other disciplines of medicine had already moved into the molecular era, but this meeting represented a major shift for the field of cardiovascular research. Increasingly, investigators were taking advantage of the new tools afforded them by discoveries in molecular biology to answer important questions about the molecular and cellular mechanisms responsible for the development of cardiovascular disease. In the ensuing 20 years, the development of new technology and its linkage with traditional biochemical
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