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Volume 355:319-322 July 20, 2006 Number 3
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Lung Recruitment in Patients with ARDS

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 by Gattinoni, L.
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To the Editor: In the April 27 issue, Gattinoni et al.1 suggest that the potential for lung recruitment in patients with acute lung injury is generally low and extremely variable among patients. We believe that a suboptimal recruitment maneuver explains such results, contradicting investigations2,3,4 that demonstrate a much larger potential for recruitment and greater homogeneity of response. Gattinoni et al. used an inspiratory plateau pressure of 45 cm of water, a pressure certainly below the critical opening pressures reported in recent studies2,3,4 in humans. The investigators also allowed expiratory pressures to repeatedly fall to 5 cm of water, a pressure . . . [Full Text of this Article]


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