Jaume Ordi, M.D., Pedro L. Alonso, M.D., Julian de Zulueta, M.D., Jordi Esteban, M.D., Martin Velasco, M.D., Ernest Mas, M.D., Elias Campo, M.D., and Pedro L. Fernández, M.D.
Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.
Holy Roman Emperor Charles V (who was also King Charles I ofSpain) was one of the most powerful rulers of all time (Figure 1A).His 40-year reign (1516–1556) occurred during the transitionfrom the Middle Ages to modern times. He was a global leader,governing territories in Europe, Africa, and Asia as well asthe conquered territories of the Aztec Empire of Mexico andthe Inca Kingdom of Peru. Given this reach, he was describedas ruling an empire "in which the sun does not set." Despitethis power, Charles V had to live within the limitations . . . [Full Text of this Article]
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From the Departments of Pathology (J.O., J.E., E.C., P.L.F.), Radiology (M.V.), and Biochemistry (E.M.), and the Center of International Health (P.L.A., J.Z.), Hospital Clínic d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona.
Matsuo, H., Takada, T., Ichida, K., Nakamura, T., Nakayama, A., Ikebuchi, Y., Ito, K., Kusanagi, Y., Chiba, T., Tadokoro, S., Takada, Y., Oikawa, Y., Inoue, H., Suzuki, K., Okada, R., Nishiyama, J., Domoto, H., Watanabe, S., Fujita, M., Morimoto, Y., Naito, M., Nishio, K., Hishida, A., Wakai, K., Asai, Y., Niwa, K., Kamakura, K., Nonoyama, S., Sakurai, Y., Hosoya, T., Kanai, Y., Suzuki, H., Hamajima, N., Shinomiya, N.
(2009). Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population. Sci Transl Med
1: 5ra11-5ra11
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Couper, R. T.L., Fernandez, P. L., Alonso, P. L.
(2006). The Severe Gout of Emperor Charles V. NEJM
355: 1935-1936
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