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Volume 355:541-543 August 10, 2006 Number 6 Next

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On May 10, 2006, the regulator of assisted reproduction in the United Kingdom — the Human Fertilisation and Embryology Authority (HFEA) — decided to include susceptibilities to certain cancers in the conditions for which it will allow preimplantation genetic diagnosis (PGD).¹ In Britain, as in most of Europe, PGD refers to the removal of a single cell from an embryo generated in vitro for genetic testing to diagnose a recurrent, serious, heritable condition and thereby to avoid the implantation of affected embryos (see diagram). The technique is used by fertile couples, as an alternative to prenatal diagnosis with the . . . [Full Text of this Article]

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Prof. Braude is the head of the Department of Women's Health at King's College London, School of Medicine, London.

Related Letters:

Preimplantation Diagnosis for Genetic Susceptibility
Gibbons W. E.
Extract | Full Text | PDF  
N Engl J Med 2006; 355:2048, Nov 9, 2006. Correspondence

This article has been cited by other articles:

• Amor, D. J., Cameron, C. (2008). PGD gender selection for non-Mendelian disorders with unequal sex incidence. Hum Reprod 23: 729-734 [Abstract] [Full Text]  
• Braude, P., Flinter, F. (2007). Use and misuse of preimplantation genetic testing. BMJ 335: 752-754 [Full Text]  
• Offit, K., Sagi, M., Hurley, K. (2006). Preimplantation Genetic Diagnosis for Cancer Syndromes: A New Challenge for Preventive Medicine. JAMA 296: 2727-2730 [Full Text]  
• Gibbons, W. E. (2006). Preimplantation Diagnosis for Genetic Susceptibility. NEJM 355: 2048-2048 [Full Text]