Saccular intracranial aneurysms, abnormal focal outpouchingsof cerebral arteries, cause substantial rates of morbidity andmortality. Recently, major changes have occurred in the waywe think about and treat this disease. Previous concepts aboutthe natural history, particularly the risk of rupture of certainaneurysms, have been challenged.1,2
When this topic was the subject of a Medical Progress articlein the Journal in 1997, minimally invasive percutaneous endovasculartreatment of intracranial aneurysms (a technique known as coiling)had been introduced as an experimental procedure for patientswho were not good candidates for surgery.3 After almost a decadeof increased use . . . [Full Text of this Article]
Epidemiology and Pathophysiology
Natural History and Risk of Rupture
Medical Diagnosis and Management of Subarachnoid Hemorrhage
Clinical Presentation and Diagnosis
Imaging Methods and Options
Clinical Approach to Imaging
Acute Effects of Subarachnoid Hemorrhage
Medical Therapy
Treatment Options
Comparison of Clipping and Coiling
Risks of Clipping
Risks of Inserting Detachable Coils
Relative Risks of Coiling and Clipping
The Effects of Surgeon and Hospital Volume
Optimal Treatment of Aneurysms
Source Information
From the Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute, JFK Medical Center, Edison, N.J. (J.L.B.); the Department of Endovascular Surgery, Institute for Neurology and Neurosurgery, Roosevelt Medical Center, New York (J.K.S.); and the Department of Neurosurgery, Seattle Neuroscience Institute, Swedish Medical Center, Seattle (D.W.N.).
Address reprint requests to Dr. Brisman at the Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute at JFK Medical Center, Edison, NJ 08818, or at jbrisman@solarishs.org.
Related Letters:
Cerebral Aneurysms
Finucane F. M., Torres V. E., Pirson Y., Wiebers D. O., Whiteley W., Salman R. A.-S., Brisman J. L., Song J. K., Newell D. W.
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N Engl J Med 2006;
355:2703-2705, Dec 21, 2006.
Correspondence
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