Lung cancer is the deadliest cancer in the world. Relapses arefrequent after primary and adjuvant therapy and often evolveinto lethal metastatic disease. Currently, lung-cancer stagingrests on histopathological and clinical criteria that have onlylimited power to predict relapse and survival. A major effortto improve the control of lung cancer entails the use of molecularprofiling to characterize tumors and provide accurate predictionsof the outcome after standard or novel treatments.
Such molecular studies of lung tumors began with single or relativelysmall groups of potential prognostic markers and have progressedto microarray analyses of thousands of . . . [Full Text of this Article]
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From the Department of Thoracic/Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston.
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