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Volume 356:1069-1071 March 8, 2007 Number 10
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Bivalirudin in Acute Coronary Syndromes

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by Stone, G. W.
To the Editor: The main message of the study of bivalirudin in patients with acute coronary syndromes, reported by Stone et al. (Nov. 23 issue)1 is that, as compared with heparin or enoxaparin plus a glycoprotein IIb/IIIa inhibitor, bivalirudin alone offers a similar degree of protection against ischemic events and a significant reduction in bleeding complications. Most of the benefit of bivalirudin alone was associated with the lower rate of catheterization-related hemorrhage (0.8% with bivalirudin alone vs. 2.5% in the other two groups). Given the importance of bleeding complications for the interpretation of the results, it is surprising that no . . . [Full Text of this Article]



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