The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Clinical Implications of Basic Research
PreviousPrevious
Volume 356:1169-1171 March 15, 2007 Number 11
NextNext

Structural Variation in the Human Genome
James R. Lupski, M.D., Ph.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Commentary
-Perspective
 by Christensen, K.

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-PubMed Citation
The completion of the Human Genome Project was a remarkable feat and provided 3 billion bases of reference nucleotides for comparative studies. An analogy often used to conceptualize human genetic information is that of an encyclopedia, in which each volume of the set would represent 1 of the 23 pairs of human chromosomes. Sections within each volume would represent the (approximately) 25,000 genes of the human genome, and letters of the alphabet would represent the individual bases of DNA encoding specific amino acids that are the building blocks of proteins. To date, the molecular medicine model that is promulgated in . . . [Full Text of this Article]


Source Information

From the Departments of Molecular and Human Genetics and Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston.


This article has been cited by other articles:



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.