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Previous Volume 356:1172-1173 March 15, 2007 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In their report on the use of inactivated and live attenuated influenza vaccines to prevent antigenically drifted influenza, Ohmit et al. (Dec. 14 issue)¹ conclude that the live attenuated vaccine was less efficacious than the inactivated vaccine in their study population of healthy adults. This conclusion is not warranted, for three reasons. First, the study was not a head-to-head comparison of the two vaccines. The design was actually that of two separate studies: a comparison of inactivated vaccine with injectable placebo and a comparison of live attenuated vaccine with intranasal placebo. Second, 1800 participants were estimated to . . . [Full Text of this Article]

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