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FOCUS ON RESEARCH Previous Volume 356:1204-1205 March 22, 2007 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Perspective Perspective by Chang, L.-Y. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Chang, L.-Y. PubMed Citation

More than 90 human enterovirus serotypes have now been identified in three distinct waves of discovery. The three poliovirus serotypes were first isolated from nonhuman primates in the course of painstaking experiments performed during the first half of the 20th century. The use of small laboratory animals and the advent of cell culture in midcentury led to the description of 61 more enteroviruses that we know as coxsackieviruses, echoviruses, and the "newer" enteroviruses. The application of polymerase chain reaction and genomic sequencing has recently permitted characterization of approximately 30 previously unidentified enterovirus serotypes and undoubtedly will uncover more.

Enterovirus 71 . . . [Full Text of this Article]

Source Information

Dr. Modlin is chair of the Department of Pediatrics at Dartmouth Medical School, Lebanon, NH.

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