Case 9-2007 -- A 27-Year-Old Woman with Pain and Swelling of the Legs

doi:10.1056/NEJMcpc079003

Volume 356:1252-1259		March 22, 2007		Number 12

Case 9-2007 — A 27-Year-Old Woman with Pain and Swelling of the Legs

Jean-Michel Vallat, M.D., Didier P. Cros, M.D., and E. Tessa Hedley-Whyte, M.D.

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Presentation of Case

A 27-year-old woman was seen in the neurology clinic becauseof pain and swelling in her feet. She had been well until approximately5 months earlier, when swelling of her ankles and lower legsdeveloped that was worse on the left side, varied in severityfrom day to day, and was not affected by position. Approximately6 weeks later, she was awakened from sleep by burning and stingingpain on the dorsal aspect of her left foot, which was aggravatedby pressure and lasted for 3 to 4 hours. The next day, she notedtingling in the dorsum of her . . . [Full Text of this Article]

Differential Diagnosis

Sensorimotor Neuropathy

Vasculitic Neuropathy

Sjögren's Syndrome

Clinical Diagnosis

Dr. Jean-Michel Vallat's Diagnosis

Pathological Discussion

Anatomical Diagnosis

Source Information

From the Department of Neurology and Neuropathology, University of Limoges, Limoges, France (J.-M.V.); the Department of Neurology (D.P.C.), and the Division of Neuropathology, Department of Pathology (E.T.H.-W.), Massachusetts General Hospital, Boston; and the Departments of Neurology (D.P.C., E.T.H.-W.) and Pathology (E.T.H.-W.), Harvard Medical School, Boston.