Blood transfusion has for years been considered to have obviousclinical benefits and to be a relatively low-risk procedure.Not until the early 1980s did transfusion practices begin tocome under systematic scrutiny. Initially, this trend was drivenby concern about transfusion-related infection, particularlyby human immunodeficiency virus, but advances in transfusionmedicine have greatly decreased the risk of transmission ofviruses by transfused blood. Now, other concerns theeffects of transfusion on the immune system, transfusion-relatedacute lung injury, and the age of transfused blood drivethe debate over transfusion practice and have led to methodicalexaminations . . . [Full Text of this Article]
Source Information
From the Section of Critical Care Medicine, DartmouthHitchcock Medical Center, Lebanon, NH (H.L.C.); and the Division of General Internal Medicine, University of Medicine and Dentistry of New JerseyRobert Wood Johnson Medical School, New Brunswick (J.L.C.).
This article has been cited by other articles:
Reynolds, J. D., Ahearn, G. S., Angelo, M., Zhang, J., Cobb, F., Stamler, J. S.
(2007). S-nitrosohemoglobin deficiency: A mechanism for loss of physiological activity in banked blood. Proc. Natl. Acad. Sci. USA
104: 17058-17062
[Abstract][Full Text]