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Volume 356:1681-1684 April 19, 2007 Number 16
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Persistent Coronary Occlusion after Myocardial Infarction

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by Hillis, L. D.
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by Hochman, J. S.
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To the Editor: The Occluded Artery Trial (OAT), reported by Hochman et al. (Dec. 7 issue),1 compared percutaneous coronary intervention (PCI) with stent placement and optimal medical therapy with optimal medical therapy alone in patients who had persistent coronary occlusion after myocardial infarction. This report and the group's earlier report on the trial design2 indicate that the study was designed to have 90% power to detect a 25% reduction in the rate of the primary end-point event — a composite of death, myocardial reinfarction, or New York Heart Association (NYHA) class IV heart failure — in patients undergoing PCI, assuming . . . [Full Text of this Article]



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