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Volume 356:1710 April 26, 2007 Number 17
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Adjunctive Antidepressants for Bipolar Depression

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by Belmaker, R.H.

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by Sachs, G. S.
The risks and benefits of standard antidepressants for patients with bipolar disorder are not well understood. In this randomized, placebo-controlled trial of patients with bipolar disorder, all of whom received a mood stabilizer, adjunctive treatment with an antidepressant did not reduce the symptoms of bipolar depression or increase the risk of mania.



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