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Previous Volume 356:1776-1778 April 26, 2007 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Of all the public health measures against infections, vaccination is arguably the most cost-effective. Most successful vaccines can be divided into two types — live attenuated vaccines and nonreplicating vaccines. The nonreplicating vaccines, such as the hepatitis B vaccine, usually consist of components of the pathogen. These are called "subunit vaccines." Critical to the protective effect of subunit vaccines are additives called adjuvants, which amplify the immune response. Currently, an aluminum salt–based substance called alum and an oil-based substance called MF59 are two adjuvants licensed for clinical use. Adjuvants are extremely important in generating a robust immune response, and yet . . . [Full Text of this Article]

Source Information

From the Emory Vaccine Center, Emory University, Atlanta.

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