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Previous Volume 356:1862-1869 May 3, 2007 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 58-year-old man presents with a 2-week history of progressive dyspnea on exertion, neck swelling, decreased appetite, and fatigue. There is no history of syncope or dysphagia. He smoked cigarettes until 5 years ago. The physical examination reveals a heart rate of 105 beats per minute, a respiratory rate of 20 breaths per minute, and superficial vascular distention over the neck, chest, . . . [Full Text of this Article]

The Clinical Problem

Anatomy and Physiology

Etiologic Factors

Strategies and Evidence

Clinical Evaluation

            Imaging

Management

            Supportive Care and Medical Management

            Radiotherapy

            Systemic Chemotherapy

            Placement of an Intravascular Stent

            Surgery

Durability of Response

Areas of Uncertainty

Guidelines from Professional Societies

Conclusions and Recommendations

Source Information

From the Departments of Therapeutic Radiology (L.D.W.) and Surgery (F.C.D.), Yale University School of Medicine; and the Yale Comprehensive Cancer Center (L.D.W., F.C.D.) — both in New Haven, CT; and the Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, and Weill Medical College of Cornell University, New York (J.Y.).

Address reprint requests to Dr. Wilson at the Department of Therapeutic Radiology, Yale University School of Medicine, HRT 132, 333 Cedar St., New Haven, CT 06520, or at lynn.wilson@yale.edu.

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