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Previous Volume 356:1880-1882 May 3, 2007 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The pathogenesis of an acute myocardial infarction consists of the rupture of atherosclerotic plaque, followed by a sudden thrombotic coronary occlusion. Pioneering studies performed more than 40 years ago, even before there was full recognition of the underlying pathobiology, showed that nonselective intracoronary fibrinolysis can restore perfusion to the jeopardized vascular territory.¹ Primary percutaneous coronary intervention (PCI) has now emerged as the optimal mode of reperfusion therapy, if performed by an experienced team within 90 minutes after the first medical contact. Primary PCI results in patency of the occluded artery in almost all patients and in normalization of epicardial perfusion, . . . [Full Text of this Article]

Source Information

From the Department of Cardiology, Academic Medical Center, Amsterdam.

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