The availability of a "cancer vaccine" has elicited enormousenthusiasm from the medical community and the public, culminatingin advocacy for mandatory vaccination against human papillomavirus(HPV) and a recommendation from the Centers for Disease Controland Prevention (CDC) that 30 million girls and women betweenthe ages of 11 and 26 years in the United States be vaccinated.1Previous reports2,3 showed a remarkable 100% efficacy of a quadrivalentvaccine targeting HPV types 6, 11, 16, and 18 on outcomes relatedto vaccine HPV types in women with no evidence of previous exposureto those types. Since HPV types 16 . . . [Full Text of this Article]
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From the Departments of Obstetrics, Gynecology and Reproductive Sciences (G.F.S., K.S.-M.), Epidemiology and Biostatistics (G.F.S.), and the Comprehensive Cancer Center (G.F.S., K.S.-M.), University of California, San Francisco, San Francisco.
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Human Papillomavirus Vaccine
Miller N. B., Raychaudhuri G., Toerner J. G., Suba E. J., Raab S. S., the Viet/American Cervical Cancer Prevention Project , Garland S. G., Koutsky L. A., Sawaya G. F., Smith-McCune K., Agosti J. M., Goldie S. J.
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N Engl J Med 2007;
357:1154-1156, Sep 13, 2007.
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