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Previous Volume 356:1993-1995 May 10, 2007 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Editorial by Baden, L. R. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article Related Article by D'Souza, G. PubMed Citation

Each year, almost 650,000 patients worldwide receive the diagnosis of head and neck cancer and some 350,000 die from this disease.¹ Nearly 90% of these cancers are squamous-cell carcinomas. The two main causative factors in approximately 80% of oral, oropharyngeal, and laryngeal carcinomas are smoking and alcohol use. Consumption of vegetables and fruit may modulate the carcinogenic effects of tobacco and alcohol, whereas low body-mass index increases the risk of oral cancer.² The idea that human papillomavirus (HPV) plays a role in these cancers has been under investigation for at least 20 years.

It is widely accepted that HPV causes . . . [Full Text of this Article]

Source Information

From the Department of Oral Pathology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.

This article has been cited by other articles:

• Ukpo, O. C., Moore, E. J., Smith, D. I., Williams, H., Higgins, C. D., Crawford, D. H., Braakhuis, B. J., Snijders, P. J., Leemans, C. R., Gillison, M. L. (2007). Human Papillomavirus and Oropharyngeal Cancer. NEJM 357: 1156-1158 [Full Text]  
• Baden, L. R., Curfman, G. D., Morrissey, S., Drazen, J. M. (2007). Human Papillomavirus Vaccine -- Opportunity and Challenge. NEJM 356: 1990-1991 [Full Text]