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Volume 356:2005-2006 May 10, 2007 Number 19
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The Incidentally Discovered Adrenal Mass

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by Young, W. F.
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To the Editor: The Clinical Practice article by Young (Feb. 8 issue),1 on the incidentally discovered adrenal mass, provides a personal view of how to approach this clinical problem, but it does not mention relevant guidelines from a recent international symposium.2,3 An important recommendation endorsed at the meeting was that initial testing for pheochromocytoma include the measurement of fractionated metanephrines in plasma, urine, or both. This recommendation recognizes that a missed diagnosis (due to inadequate sensitivity) can have catastrophic consequences for the patient. Young emphasizes specificity and in this respect suggests that urinary measurement is preferable to plasma measurement. However, . . . [Full Text of this Article]



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