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Volume 356:2006-2007 May 10, 2007 Number 19
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Urine Fluorescence in Ethylene Glycol Poisoning

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 by McStay, C. M.
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To the Editor: With regard to the Image in Clinical Medicine by McStay and Gordon (Feb. 8 issue),1 the presence of urine fluorescence can be short lived, less than 4 hours from the time of ingestion.2 This brief duration poses the potential for false negative results. Not all brands of antifreeze contain fluorescein as a colorant for the detection of radiator leaks. Other researchers have reported that urine specimens from children may fluoresce without an exposure to antifreeze.3,4 A database lists 148 substances, including a number of drugs, food products, toxins, and endogenous compounds, that can contribute to urine fluorescence . . . [Full Text of this Article]




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