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Volume 356:2011-2012 May 10, 2007 Number 19

The Sperm Cell: Production, Maturation, Fertilization, Regeneration

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Edited by Christopher De Jonge and Christopher Barratt. 359 pp., illustrated. New York, Cambridge University Press, 2006. $120. ISBN 978-0-521-85397-2.

In 1992, the announcement that pregnancies had been achieved after intracytoplasmic injection of a single sperm into an oocyte sent shock waves through the andrology community. Was the male gamete's role in reproduction now merely to contribute chromosomes? Was there any benefit to the clinical investigation of male infertility? Leaders in the field of andrology, including the editors of and several contributors to The Sperm Cell, argued that intracytoplasmic sperm injection (ICSI) was simply a tool to assist fertilization for men with unexplained or undiagnosed subfertility and would not replace the need to further our understanding of sperm function. Indeed, . . . [Full Text of this Article]




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