To the Editor: In their article on the use of microscopic-observationdrug-susceptibility (MODS) culture for the diagnosis and directdetection of multidrug-resistant tuberculosis, Moore et al.(Oct. 12 issue)1 state that MODS culture offers faster and moresensitive results than existing gold-standard methods. Thisstudy is one of the few performed in a target population witha rather simple and inexpensive method that seems to be appropriatefor countries with limited resources.
However, we would like to stress that there are other optionsthat have recently been described2 and are currently under evaluation.As compared with MODS culture, the nitrate . . . [Full Text of this Article]
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